15663-27-1
- Product Name：Cisplatin
- Molecular Formula：Cl2H6N2Pt
- Purity：99%
- Molecular Weight：300.047
Product Details;
CasNo： 15663-27-1
Molecular Formula： Cl2H6N2Pt
Appearance： Orange-yellow to deep yellow solid or powder
Manufacturer supply top purity Cisplatin 15663-27-1 with ISO standards We supply high quality Cisplatin (CAS 15663-27-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Cisplatin ?
Cisplatin is Orange-yellow to deep yellow solid or powder, while it's Molecular Formula is Cl2H6N2Pt. antitumor agent
What is the CAS number for Cisplatin ?
The CAS number of Cisplatin is 15663-27-1.
More information of Cisplatin 15663-27-1 are:
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Synonyms |
Neoplatin;Platosin;cis-dichlorodi-ammine platinum(ii);cis-Diammineplatinum(II) dichloride;cis-Dichlorodiamminoplatinum(II);CPDD;cisPt(II);cis-Platinum(II) diaminodichloride;Platinum(II), diamminedichloro-, cis-;Biocisplatinum;Cisplatyl;DDP (antitumor agent);Cisplatinum;azane; platinum(+2) cation; dichloride; |
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CAS Number |
15663-27-1 |
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Molecular Formula |
Cl2H6N2Pt |
|
Molecular Weight |
300.047 |
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Density |
3.7 g/cm3 |
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Melting Point |
340 °C (dec.)(lit.) |
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HS CODE |
2843 90 90 |
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PSA |
24.72000 |
|
LogP |
2.02430 |
What is Cisplatin (15663-27-1) used for?
Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis. It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding. Cisplatin halts the cell cycle at the G2/M phase in vitro and is active against murine tumors transplanted into mice and in mouse xenograft models, including a reduction in tumor growth in a model of squamous cell carcinoma of the head and neck when administered at doses ranging from 7.5 to 12.5 mg/kg. Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 μM), blocking protein splicing and cell growth. Formulations containing cisplatin have been used, alone and in combination therapy, in the treatment of a variety of cancers.
InChI:InChI=1/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
Articles related to Cisplatin:
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Article |
Source |
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Copper-free click-chemistry platform to functionalize cisplatin prodrugs |
Pathak, Rakesh K.,McNitt, Christopher D.,Popik, Vladimir V.,Dhar, Shanta , p. 6861 - 6865 (2014) |
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Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs |
Ravera, Mauro,Gabano, Elisabetta,Zanellato, Ilaria,Bonarrigo, Ilaria,Alessio, Manuela,Arnesano, Fabio,Galliani, Angela,Natile, Giovanni,Osella, Domenico , p. 1 - 8 (2015) |
How to get the best price on Cisplatin?
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