3184-13-2
- Product Name：L(+)-Ornithine hydrochloride
- Molecular Formula：C5H13ClN2O2
- Purity：99%
- Molecular Weight：168.623
Product Details;
CasNo： 3184-13-2
Molecular Formula： C5H13ClN2O2
Appearance： white crystalline powder
Manufacturer supply top purity L(+)-Ornithine hydrochloride 3184-13-2 with GMP standards
- Molecular Formula:C5H13ClN2O2
- Molecular Weight:168.623
- Appearance/Colour:white crystalline powder
- Vapor Pressure:0.00015mmHg at 25°C
- Melting Point:245 °C
- Refractive Index:24 ° (C=4, 6mol/L HCl)
- Boiling Point:308.7oC at 760 mmHg
- Flash Point:140.5oC
- PSA：89.34000
- Density:1.57 g/cm3
- LogP:1.33980
L(+)-Ornithine hydrochloride(Cas 3184-13-2) Usage
|
Flammability and Explosibility |
Notclassified |
|
Biochem/physiol Actions |
L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain. |
|
Safety Profile |
Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. |
|
Purification Methods |
Likely impurities are citrulline, arginine and D-ornithine. Crystallise the monohydrochloride from water by adding 4volumes of EtOH and dry it in a vacuum desiccator over fused CaCl2. [Rivard Biochemical Preparations 3 98 1955.] The dihydrochloride [6211-16-1] has m 202-203o and [ ] D +18.4o (c 2.3, 6N HCl) after recrystallisation from MeOH/Et2O [Zaoral & Rudinger Collect Czech Chem Commun 24 2009 1959]. [Beilstein 4 IV 2644.] |
|
Used in Pharmaceutical Industries |
In the pharmaceutical sector, L-Ornithine hydrochloride serves as a nutritional supplement, supplying the body with ornithine and potentially offering health benefits, especially in sports nutrition and performance products. L-ornithine hydrochloride is employed in medical treatments, aiding in amino acid metabolism regulation and urea cycle management, particularly in liver and kidney disease therapies.[2] |
|
Used in Sports Nutrition Industries |
Recent research indicates its potential in enhancing human growth hormone secretion post-strength training and improving performance during exhaustive ergometer bicycle exercises, showcasing its versatility in sports nutrition and performance enhancement. |
|
Used in Cosmetic Industries |
L-Ornithine hydrochloride is utilized in cosmetics for its purported moisturizing and antioxidant properties, contributing to skin health and care. |
|
Aroma threshold values |
Low strength odor, green type. |
|
Taste threshold values |
Very mild sweet taste at 500.00 ppm in water. |
|
General Description |
L-Ornithine is the functional metabolite of L-arginine. |
InChI:InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m0/s1
3184-13-2 Relevant articles
Thermochemistry of the hydrolysis of L-arginine to (L-citrulline + ammonia) and of the hydrolysis of L-arginine to (L-ornithine + urea)
Tewari, Y. B.,Kishore, N.,Margolis, S. A.,Goldberg, R. N.,Shibatani, T.
, p. 293 - 305 (1993)
Molar enthalpies of reaction for the hyd...
Highly enantioselective synthesis of non-natural aliphatic α-amino acids via asymmetric hydrogenation
Ji, Jianjian,Chen, Caiyou,Cai, Jiayu,Wang, Xinrui,Zhang, Kai,Shi, Liyang,Lv, Hui,Zhang, Xumu
supporting information, p. 7624 - 7627 (2015/07/15)
By employing a rhodium-Duanphos complex ...
Synthesis of (ε-13C-,ε-15N)-enriched L-lysine - Establishing schemes for the preparation of all possible 13C and 15N isotopomers of L-lysine, L-ornithine, and L-proline
Siebum, Arjan H. G.,Tsang, Robert K. F.,Van Der Steen, Rob,Raap, Jan,Lugtenburg, Johan
, p. 4391 - 4396 (2007/10/03)
In this paper we describe a simple synth...
Polyunsaturated fatty acid derivatives, pharmaceutical compositions containing the same, method for the preparation thereof, and their use as medicament
-
, (2008/06/13)
The compounds of the Formula (I) STR1 wh...
3184-13-2 Process route
-
-
1119-34-2
L-arginine hydrochloride
-
-
3184-13-2,36630-89-4
L-ornithine hydrochloride
-
-
57-13-6
urea
| Conditions | Yield |
|---|---|
|
With
dipotassium hydrogenphosphate; phosphoric acid; water;
at 25 - 37.1 ℃;
Thermodynamic data;
ΔH; arginase (EC 3.5.3.1); var. pH and ionic strength;
|
-
-
(R)-methyl 2-acetamido-7-chloroheptanoate
-
-
1069-31-4,3184-13-2,6211-16-1,15160-12-0,16682-12-5,20724-48-5,22834-83-9,26982-21-8,66837-02-3,99815-05-1,36630-89-4
(R)-2,5-diaminopentanoic acid dihydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
for 10h;
Reflux;
|
85% |
3184-13-2 Upstream products
-
1119-34-2
L-arginine hydrochloride
-
26302-89-6
L-ornithine tert-butyl ester
-
271601-28-6
1,1-dimethylethyl 4-cyano-(2S)-[(diphenylmethylene)amino]butanoate
-
824956-17-4
tert-butyl 2-amino-4-cyanobutanoate
3184-13-2 Downstream products
-
13650-49-2
Nδ-(tert-butoxycarbonyl)-L-ornithine
-
3304-51-6
N-carboxybenzyl-L-ornithine
-
35748-65-3
(+)-S-2-amino-5-iodoacetamidopentanoic acid
-
18830-00-7
Nδ-(4-nitrobenoyl)ornithine
Relevant Products
-
Amlodipine besylateCAS：111470-99-6
-
Sodium alginateCAS：9005-38-3
-
CisplatinCAS：15663-27-1
