124750-99-8
- Product Name：Losartan potassium
- Molecular Formula：C22H22ClKN6OK
- Purity：99%
- Molecular Weight：461.008
Product Details;
CasNo： 124750-99-8
Molecular Formula： C22H22ClKN6OK
Appearance： white to off-white crystalline powder
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What is the Losartan potassium ?
Losartan potassium is white to off-white crystalline powder, while it's Molecular Formula is C22H22ClKN6OK. Coronary vasodilator used in the diagnosis of coronary heart disease (adenosine A2A agonist).
What is the CAS number for Losartan potassium ?
The CAS number of Losartan potassium is 124750-99-8.
More information of Losartan potassium 124750-99-8 are:
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Synonyms |
Lotim;L-158086;Ocsaar;Losacor;Tenopres;Lortaan;Losaprex;Hyzaar;Niten;DuP 753;Losartan monopotassium salt;MK 954;Lorzaan;Cozaar;Llosartan;Losartanpotassium;Lorzaar;1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt;2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium;MK-0954;Losacar;MK 0954;potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;Cozaar (TN); |
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CAS Number |
124750-99-8 |
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Molecular Formula |
C22H22ClKN6OK |
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Molecular Weight |
461.008 |
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Density |
0.986g/mLat 25°C(lit.) |
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Melting Point |
?69°C(lit.) |
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Boiling Point |
682 °C at 760mmHg |
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Flash Point |
366.3 °C |
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HS CODE |
2933290000 |
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PSA |
89.61000 |
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LogP |
3.89590 |
What is Losartan potassium (124750-99-8) used for?
Losartan potassium is the first potent and selective non-peptide angiotensin II (AT II) AT1 receptor antagonist introduced to the market as a once-daily oral antihypertensive. It is efficacious and long lasting in controlling blood pressure in spontaneous hypertensive rats, in patients with essential hypertension in addition to those patients with renal impairment. Since losartan functions by competitive antagonism at the level of receptor, which represents the most direct way of selectively inhibiting the renin-angiotensin system (RAS) independent of the source of AT II, its use has been reported to be free of the coughing side effect exhibited by the ACE inhibitors. In contrast to calcium channel blockers, losartan does not appear to cause ankle edema, headache and tachycardia. It is also reported to be in clinical trials for the treatment of heart failure. Other reports indicate that losartan may have potential efficacy as an anxiolytic, an antiglaucoma agent, in addition to in providing protection against stroke and in preventing the myointimal proliferative response of the vascular wall after coronary angioplasty and surgery.
InChI:InChI=1/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,25,26,27,28);/q-1;+1
Articles related to Losartan potassium:
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Article |
Source |
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COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING SALT SENSITIVITY OF BLOOD PRESSURE |
- , (2015/02/05) |
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An efficient, commercially viable, and safe process for preparation of losartan potassium, an angiotensin II receptor antagonist |
Madasu, Suri Babu,Vekariya,Koteswaramma, Ch,Islam, Aminul,Sanasi, Paul Douglas,Korupolu, Raghu Babu , p. 2025 - 2030 (2013/02/25) |
How to get the best price on Losartan potassium?
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