51-21-8
- Product Name：5-Fluorouracil
- Molecular Formula：C4H3FN2O2
- Purity：99%
- Molecular Weight：130.078
Product Details;
CasNo： 51-21-8
Molecular Formula： C4H3FN2O2
Appearance： white to nearly white crystalline powder
Manufacturer supply high quality 5-Fluorouracil 51-21-8 with ISO standards We supply high quality 5-Fluorouracil (CAS 51-21-8), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the 5-Fluorouracil ?
5-Fluorouracil is white to nearly white crystalline powder, while it's Molecular Formula is C4H3FN2O2. A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis
What is the CAS number for 5-Fluorouracil ?
The CAS number of 5-Fluorouracil is 51-21-8.
More information of 5-Fluorouracil 51-21-8 are:
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Synonyms |
Ro-2-9757;Phtoruracil;2,4(1H,3H)-Pyrimidinedione,5-fluoro-;Phthoruracil;5-Fluoro-2,4(1H, 3H)-pyrimidinedione;Fluoroplex;5-Fluoracyl;Efudex;Effluderm (free base);U 8953;Adrucil;Efurix;5-Ftouracyl;U-8953;Arumel;Kecimeton;Fluro Uracil;Uracil, 5-fluoro- (VAN 8CI);Fluracil;Efudix;Ro 2-9757;Fluracilum;5-FU;5-Fluoro-2,4-pyrimidinedione; |
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CAS Number |
51-21-8 |
|
Molecular Formula |
C4H3FN2O2 |
|
Molecular Weight |
130.078 |
|
Density |
1.53 g/cm3 |
|
Melting Point |
282-286 °C (dec.)(lit.) |
|
Boiling Point |
401.4 °C at 760 mmHg |
|
Flash Point |
196.5 °C |
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HS CODE |
2933.59 |
|
PSA |
65.72000 |
|
LogP |
-0.79770 |
|
Pka |
pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain) |
What is 5-Fluorouracil (51-21-8) used for?
5-Fluorouracil (5-FU) is a prodrug form of the thymidylate synthase inhibitor fluorodeoxyuridylate (FdUMP). It is also converted to the active metabolites FUTP and FdUTP, which induce RNA and DNA damage, respectively. In vivo, 5-FU (15 mg/kg) when administered in combination with docetaxel reduces tumor growth in B88 and CAL 27 oral squamous cell carcinoma (OSCC) mouse xenograft models. Formulations containing 5-FU have been used in the treatment of colorectal, breast, gastric, and pancreatic cancers.
InChI:InChI=1/C4H3FN2O2/c5-7-2-1-3(8)6-4(7)9/h1-2H,(H,6,8,9)
Articles related to 5-Fluorouracil:
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Article |
Source |
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Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase |
Shea, Tara A.,Burburan, Paola J.,Matubia, Vivian N.,Ramcharan, Sandy S.,Rosario Jr., Irving,Parkin, David W.,Stockman, Brian J. , p. 1080 - 1084 (2014) |
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Solid-phase synthesis of biocompatible N-heterocyclic carbene-Pd catalysts using a sub-monomer approach |
Cherukaraveedu, Durgadas,Cowling, Paul T.,Birch, Gavin P.,Bradley, Mark,Lilienkampf, Annamaria , p. 5533 - 5537 (2019) |
How to get the best price on 5-Fluorouracil?
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