71-00-1

  • Product Name:Histidine
  • Molecular Formula:C6H9N3O2
  • Purity:99%
  • Molecular Weight:155.156
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Product Details;

CasNo: 71-00-1

Molecular Formula: C6H9N3O2

Appearance: white crystalline powder

Factory Supply industrial standard Histidine 71-00-1 In Stock

  • Molecular Formula:C6H9N3O2
  • Molecular Weight:155.156
  • Appearance/Colour:white crystalline powder 
  • Melting Point:282 °C (dec.)(lit.) 
  • Refractive Index:13 ° (C=11, 6mol/L HCl) 
  • Boiling Point:458.9 °C at 760 mmHg 
  • PKA:1.91±0.10(Predicted) 
  • Flash Point:231.3 °C 
  • PSA:92.00000 
  • Density:1.423 g/cm3 
  • LogP:0.06440 

Histidine(Cas 71-00-1) Usage

Chemical Description

Histidine is an alpha-amino acid containing an isopyrazole ring. It is a constituent amino acid of body proteins and is found in some functional proteins such as histones and hemoglobin.
Histidine residues and isopyrazole rings are components of enzyme proteins and functional parts of certain proteins. It's structure includes an α-amino group, a carboxylic acid group, and an imidazole side chain.Under physiological conditions, the amino group is protonated, and the carboxylic group is deprotonated.

Physiological Functions

Histidine is a natural chelating agent and is involved in the structure and function of many enzymes.
Free histidine, small peptides containing histidine, and histamine generated from histidine decarboxylation all have specific physiological functions.
It plays a role in metabolism and affects various metabolic processes in the body.

Molecular Interactions

The versatility of histidine in molecular interactions arises from its unique molecular structure. Histidine's imidazole side chain can engage in various molecular interactions, including cation-π interaction, π-π stacking interaction, hydrogen-π interaction, coordinate bond interaction, and hydrogen bond interaction. These interactions contribute to histidine's role in protein structure, enzymatic function, and other physiological processes.

Nutritional and Therapeutic Uses

Histidine is considered an essential amino acid for young children but non-essential for adults. It has been used as a nutritional supplement in various conditions such as rheumatoid arthritis, anaemia in chronic renal failure, fatigue during exercise, ageing-related disorders, metabolic syndrome, atopic dermatitis, ulcers, inflammatory bowel diseases, ocular diseases, and neurological disorders.

General Description

Histidine is an essential amino acid that is crucial for the synthesis of proteins in the human body. It plays a key role in the growth and repair of tissues, as well as in the maintenance of the myelin sheath that protects nerve cells. Additionally, histidine is a precursor for the synthesis of histamine, which is involved in various physiological processes such as digestion, immune response, and inflammation. It also acts as a metal chelator, binding with heavy metals to aid in their excretion from the body. Histidine is found in various protein-rich foods such as meat, fish, dairy products, and certain grains, making it an important nutrient for overall health and well-being.

InChI:InChI:1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)

71-00-1 Relevant articles

An unprecedented trans-oriented product from the cleavage of a dipeptide.

Saha, Manas K,Bernal, Ivan

, p. 612 - 613 (2003)

An unusual trans cleavage reaction was o...

High-throughput screening for the asymmetric transformation reaction of L-histidine to D-histidine by capillary array electrophoresis

Wang, Jun,Liu, Kaiying,Sun, Guangming,Bai, Jiling,Wang, Li

, p. 901 - 904 (2006)

Asymmetric transformation reaction of L-...

Direct monitoring of biocatalytic deacetylation of amino acid substrates by1H NMR reveals fine details of substrate specificity

De Cesare, Silvia,McKenna, Catherine A.,Mulholland, Nicholas,Murray, Lorna,Bella, Juraj,Campopiano, Dominic J.

supporting information, p. 4904 - 4909 (2021/06/16)

Amino acids are key synthetic building b...

Fluorinated S-Adenosylmethionine as a Reagent for Enzyme-Catalyzed Fluoromethylation

Bauer, Carsten,Liao, Cangsong,Peng, Jiaming,Seebeck, Florian P.

, p. 27178 - 27183 (2021/11/16)

Strategic replacement of protons with fl...

Safe and Effective Method of Treating Ulcerative Colitis with Anti-IL12/IL23 Antibody

-

, (2020/04/10)

Described are methods and compositions f...

A green-by-design bioprocess for l-carnosine production integrating enzymatic synthesis with membrane separation

Yin, Dong-Ya,Pan, Jiang,Zhu, Jie,Liu, You-Yan,Xu, Jian-He

, p. 5971 - 5978 (2019/11/14)

l-Carnosine (l-Car, β-alanyl-l-histidine...

71-00-1 Process route

Hizikia fusiformis lectine

Hizikia fusiformis lectine

L-alanin
56-41-7,25191-17-7,18875-37-1

L-alanin

L-Cysteine
52-90-4

L-Cysteine

L-threonine
72-19-5,134357-96-3,7013-32-3,82822-12-6

L-threonine

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

L-isoleucine
73-32-5,959215-79-3,18875-42-8

L-isoleucine

L-methionine
63-68-3,26062-47-5,58576-49-1

L-methionine

L-lysine
56-87-1,3506-25-0

L-lysine

L-glutamic acid
56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6

L-glutamic acid

L-arginine
74-79-3,25212-18-4

L-arginine

L-phenylalanine
63-91-2,25191-15-5,658-69-5,67675-33-6

L-phenylalanine

L-tyrosine
60-18-4,18875-48-4,25619-78-7,30704-25-7

L-tyrosine

<i>L</i>-proline
147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7

L-proline

L-histidine
71-00-1

L-histidine

Conditions
Conditions Yield
With hydrogenchloride; In water; at 100 ℃; for 24h; Inert atmosphere; Sealed tube;
type I collagen from Bester sturgeon scales

type I collagen from Bester sturgeon scales

L-alanin
56-41-7,25191-17-7,18875-37-1

L-alanin

L-valine
72-18-4,25609-85-2,7004-03-7,921-10-8

L-valine

L-serin
56-45-1,83245-15-2

L-serin

L-threonine
72-19-5,134357-96-3,7013-32-3,82822-12-6

L-threonine

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

L-isoleucine
73-32-5,959215-79-3,18875-42-8

L-isoleucine

L-methionine
63-68-3,26062-47-5,58576-49-1

L-methionine

L-lysine
56-87-1,3506-25-0

L-lysine

L-Aspartic acid
56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3

L-Aspartic acid

(5R)-5-hydroxy-L-lysine
504-91-6,1190-94-9,3506-26-1,6000-08-4,18899-29-1,18899-30-4,18899-31-5,52153-41-0,78088-29-6,28902-93-4

(5R)-5-hydroxy-L-lysine

L-arginine
74-79-3,25212-18-4

L-arginine

S,S-cystine
349-46-2

S,S-cystine

L-phenylalanine
63-91-2,25191-15-5,658-69-5,67675-33-6

L-phenylalanine

L-tyrosine
60-18-4,18875-48-4,25619-78-7,30704-25-7

L-tyrosine

glycine
56-40-6,18875-39-3,25718-94-9

glycine

<i>L</i>-proline
147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7

L-proline

4R-4-hydroxyproline
51-35-4,30724-02-8

4R-4-hydroxyproline

L-histidine
71-00-1

L-histidine

Conditions
Conditions Yield
With hydrogenchloride; water; at 110 ℃; for 24h;

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