
134678-17-4
- Product Name:Lamivudine
- Molecular Formula:C8H11N3O3S
- Purity:99%
- Molecular Weight:229.26
Product Details;
CasNo: 134678-17-4
Molecular Formula: C8H11N3O3S
Appearance: white crystalline powder
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What is the Lamivudine ?
Lamivudine is white crystalline powder, while it's Molecular Formula is C8H11N3O3S. Lamivudine is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children 3 months of age and older. Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.
What is the CAS number for Lamivudine ?
The CAS number of Lamivudine is 134678-17-4.
More information of Lamivudine 134678-17-4 are:
Synonyms |
Epivir; GR109714X |
CAS Number |
134678-17-4 |
Molecular Formula |
C8H11N3O3S |
Molecular Weight |
229.26 |
Density |
1.73 g/cm3 |
Melting Point |
177 °C |
Boiling Point |
475.4 °C at 760mmHg |
Flash Point |
241.3 °C |
HS CODE |
29349990 |
PSA |
115.67000 |
LogP |
-0.01290 |
Pka |
13.83±0.10(Predicted) |
What is Lamivudine (134678-17-4) used for?
Lamivudine is a new generation orally active nucleoside analog launched in the U.S.A. for use in combination with zidovudine (AZT) as a first-line therapy for patients with HIV infection. Lamivudine is rapidly converted to phosphorylated metabolites in the body which act as inhibitors and chain terminators of HIV reverse transcriptase (RT), the enzyme required for the replication of the HIV genome. Lamivudine has similar inhibitory potency to RT as AZT but is 10 times less toxic and is active against AZT-resistant strains of HIV.
InChI:InChI=1/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m1/s1
Articles related to Lamivudine:
Article |
Source |
The chemical resolution of racemic CIS-2-hydroxymethyl-5-(Cytosine-1′-YL)-1,3-oxathiolane (BCH-189) - One direct method to obtain lamivudine as anti-HIV and anti-HBV agent |
Li, Ji-zhen,Gao, Lian-xun,Ding, Meng-xian , p. 2355 - 2359 (2002) |
An Economical Route to Lamivudine Featuring a Novel Strategy for Stereospecific Assembly |
Abdiaj, Irini,Ahmad, Saeed,Burns, Justina M.,Gopalsamuthiram, Vijayagopal,Gupton, B. Frank,Krack, Rudy,McQuade, D. Tyler,Nelson, Ryan C.,Snead, David R.,Stringham, Rodger W. , p. 1194 - 1198 (2020) |
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