134678-17-4

  • Product Name:Lamivudine
  • Molecular Formula:C8H11N3O3S
  • Purity:99%
  • Molecular Weight:229.26
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Product Details;

CasNo: 134678-17-4

Molecular Formula: C8H11N3O3S

Appearance: white crystalline powder

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What is the Lamivudine ?

Lamivudine is white crystalline powder, while it's Molecular Formula is C8H11N3O3S. Lamivudine is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children 3 months of age and older. Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.

What is the CAS number for Lamivudine ?

The CAS number of Lamivudine is 134678-17-4.

More information of Lamivudine 134678-17-4 are:

Synonyms

Epivir; GR109714X

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26

Density

1.73 g/cm3

Melting Point

177 °C

Boiling Point

475.4 °C at 760mmHg

Flash Point

241.3 °C

HS CODE

29349990

PSA

115.67000

LogP

-0.01290

Pka

13.83±0.10(Predicted)

What is Lamivudine (134678-17-4) used for?

Lamivudine is a new generation orally active nucleoside analog launched in the U.S.A. for use in combination with zidovudine (AZT) as a first-line therapy for patients with HIV infection. Lamivudine is rapidly converted to phosphorylated metabolites in the body which act as inhibitors and chain terminators of HIV reverse transcriptase (RT), the enzyme required for the replication of the HIV genome. Lamivudine has similar inhibitory potency to RT as AZT but is 10 times less toxic and is active against AZT-resistant strains of HIV.

InChI:InChI=1/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m1/s1

Articles related to Lamivudine:

Article

Source

The chemical resolution of racemic CIS-2-hydroxymethyl-5-(Cytosine-1′-YL)-1,3-oxathiolane (BCH-189) - One direct method to obtain lamivudine as anti-HIV and anti-HBV agent

Li, Ji-zhen,Gao, Lian-xun,Ding, Meng-xian

, p. 2355 - 2359 (2002)

An Economical Route to Lamivudine Featuring a Novel Strategy for Stereospecific Assembly

Abdiaj, Irini,Ahmad, Saeed,Burns, Justina M.,Gopalsamuthiram, Vijayagopal,Gupton, B. Frank,Krack, Rudy,McQuade, D. Tyler,Nelson, Ryan C.,Snead, David R.,Stringham, Rodger W.

, p. 1194 - 1198 (2020)

How to get the best price on Lamivudine?

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