2627-69-2
- Product Name：AICAR
- Molecular Formula：C9H14N4O5
- Purity：99%
- Molecular Weight：258.234
Product Details;
CasNo： 2627-69-2
Molecular Formula： C9H14N4O5
Appearance： tan powder
Manufacturer supply good quality AICAR 2627-69-2 with stock We supply high quality AICAR (CAS 2627-69-2), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the AICAR ?
AICAR is tan powder, while it's Molecular Formula is C9H14N4O5. 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
What is the CAS number for AICAR ?
The CAS number of AICAR is 2627-69-2.
More information of AICAR 2627-69-2 are:
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Synonyms |
Imidazole-4-carboxamide,5-amino-1-b-D-ribofuranosyl- (6CI,7CI,8CI);1-Ribosyl-4-carboxamido-5-aminoimidazole;1-b-D-Ribofuranosyl-5-amino-4-imidazolecarboxamide;5-Amino-1-ribosyl-4-imidazolecarboxamide;5-Amino-1-b-D-ribofuranosylimidazole-4-carboxamide;5-Amino-4-imidazolecarboxamide ribofuranoside;5-Amino-4-imidazolecarboxamideriboside;5-Aminoimidazole-4-carboxamide 1-(b-D-ribofuranoside);AIC-Riboside;AICA-Riboside;Acadesine;Arasine;NSC 105823;GP 1-110; |
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CAS Number |
2627-69-2 |
|
Molecular Formula |
C9H14N4O5 |
|
Molecular Weight |
258.234 |
|
Density |
2.06 g/cm3 |
|
Melting Point |
214-215 °C |
|
Boiling Point |
726.3 °C at 760 mmHg |
|
Flash Point |
393.1 °C |
|
HS CODE |
29349990 |
|
PSA |
156.85000 |
|
LogP |
-1.54280 |
|
Pka |
13.27±0.70(Predicted) |
What is AICAR (2627-69-2) used for?
AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in vascular disease.3 ?Induces osteogenic differentiation in mesenchymal stem cells.4 Inhibits proinflammatory response in glial cells.5 Cell permeable.
InChI:InChI=1/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
Articles related to AICAR:
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Article |
Source |
|
Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase |
Firestine, Steven M.,Wu, Weidong,Youn, Hasik,Jo Davisson , p. 794 - 803 (2009) |
|
Synthesis of N-1 and ribose modified inosine analogues on solid support |
Oliviero, Giorgia,Amato, Jussara,Borbone, Nicola,D'Errico, Stefano,Piccialli, Gennaro,Mayol, Luciano , p. 397 - 400 (2007) |
How to get the best price on AICAR?
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