1401708-83-5

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1.What is the Dihexa ?

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease.

2.What is the CAS number for Dihexa ?

The CAS number of Dihexa is 1401708-83-5.

More information of Dihexa 1401708-83-5 are:

3.What is the molecular formula of Dihexa ?

The chemical formula of Dihexa is C₂₇H₄₄N₄O₅ which containing 27 Carbon atoms,44 Hydrogen atoms,4 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight, and the molecular weight of Dihexa is 504.67

4.What is Dihexa(1401708-83-5)used for?

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

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5.Top Quality Chinese Factory supply 1401708-83-5 Dihexa

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